The MitoQ story - the beginning

The MitoQ story - the beginning

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Feb 25, 2017 |2 mins to read

MitoQ was discovered in a University of Otago lab in the 1990s, when biochemist Robin Smith and mitochondrial specialist Mike Murphy figured out that regular CoQ10 was too large to cross the mitochondrial membrane — so they engineered a smaller, positively charged version that could be pulled directly into the mitochondria, delivering antioxidant protection exactly where it was needed most.

1990's - Initial Research

The MitoQ story began in a science lab at the University of Otago, New Zealand in the 1990s. Biochemist, Robin Smith and Mitochondrial Specialist, Michael Murphy, were studying mitochondria and trying to understand why taking antioxidant supplements, like CoQ10, were proving to be ineffective cures for certain diseases.

What they discovered was that regular CoQ10 supplements were too big to penetrate the very selective mitochondrial wall and whilst these supplements got into the blood-stream, they were unable to get into the mitochondria itself.

So, our scientists set about trying to create molecules that could accumulate directly inside the mitochondria and in doing so, create a more effective and powerful antioxidant.

1990's - The MitoQ Mitoquinol Discovery

The result of this research was a remarkable discovery: the scientists figured out how to create a shortened version of CoQ10 and give it a positive charge; the effect of these modifications were unique:

1. The new, positively charged molecule was instantly attractive to the negatively charged mitochondria; and

2. As a result of being a smaller compound, the molecule was able to pass directly through the mitochondrial wall and into the body of the mitochondria.

This provided a payload of free radical defense right where it was needed most and as a result, helped to support the cell and optimize the energy production process.

The discovery was initially called MitoQ10. Today, it is known as MitoQ.

2012 / 2013 - MitoQ For Sale

Our first product, MitoQ Cellular Energizing Cream Serum, was launched in Paris in 2012.

A year later saw the development of our supplement range, beginning with MitoQ 5mg (original) – the world’s first antioxidant supplement to directly target the mitochondria.

2015 / 2016 - New Formulas

From there, we realized that MitoQ Mitoquinol could be combined with additional ingredients, presenting a unique opportunity to target specific aspects of health and well-being. Our range was expanded to include new formulas, combining our base MitoQ product, with some carefully selected, premium ingredients, such as Longvida® Curcumin - to support healthy brain and digestive function, Siliphos Milk Thistle – to support healthy liver function; and Green Lip Mussel Extract – to support healthy joint function.

The world is now waking up to the importance of mitochondrial health and the remarkable discovery of MitoQ Mitoquinol.

We need energy to do the work of cells—our muscle cells, brain cells, kidney cells—everything needs energy.
Professor. Mike Murphy MitoQ Mitoquinol co-originator

At MitoQ, we are passionate about helping people revitalize, re-energize and rejuvenate every cell in their body, so they can thrive in their world. And for less than the price of a good cup of coffee per day, anyone can benefit from the amazing long-term properties of MitoQ and have confidence that they are doing the best they can for their health.

Discover the science behind MitoQ

REFERENCES

  • 1.

    Kelso, G. F., Porteous, C. M., Coulter, C. V., Hughes, G., Porteous, W. K., Ledgerwood, E. C., Smith, R. A., & Murphy, M. P. (2001). Selective targeting of a redox-active ubiquinone to mitochondria within cells: Antioxidant and antiapoptotic properties. Journal of Biological Chemistry, 276(7), 4588–4596. https://pubmed.ncbi.nlm.nih.gov/11092892/

Disclaimer: This blog contains promotional content about our products. The information provided in this blog is for educational and informational purposes only and should not be construed as medical advice. Always consult your healthcare provider with any questions you may have regarding a medical condition or health objectives.
Georgia Truman is the Scientific Affairs Manager at MitoQ, based in Hamilton, New Zealand. She leads the Mitochondrial Collaborative Research Programme (MCRP) and oversees science communications, helping bring the latest research on mitoquinol, mitochondrial health, and longevity to life for the MitoQ community. Georgia also hosts The MitoPod, MitoQ’s podcast dedicated to mitochondrial health and longevity science